In prior work, we introduced IndexTTS 2, a zero-shot neural text-to-speech foundation model comprising two core components: a transformer-based Text-to-Semantic (T2S) module and a non-autoregressive Semantic-to-Mel (S2M) module, which together enable faithful emotion replication and establish the first autoregressive duration-controllable generative paradigm. Building upon this, we present IndexTTS 2.5, which significantly enhances multilingual coverage, inference speed, and overall synthesis quality through four key improvements: 1) Semantic Codec Compression: we reduce the semantic codec frame rate from 50 Hz to 25 Hz, halving sequence length and substantially lowering both training and inference costs; 2) Architectural Upgrade: we replace the U-DiT-based backbone of the S2M module with a more efficient Zipformer-based modeling architecture, achieving notable parameter reduction and faster mel-spectrogram generation; 3) Multilingual Extension: We propose three explicit cross-lingual modeling strategies, boundary-aware alignment, token-level concatenation, and instruction-guided generation, establishing practical design principles for zero-shot multilingual emotional TTS that supports Chinese, English, Japanese, and Spanish, and enables robust emotion transfer even without target-language emotional training data; 4) Reinforcement Learning Optimization: we apply GRPO in post-training of the T2S module, improving pronunciation accuracy and natrualness. Experiments show that IndexTTS 2.5 not only supports broader language coverage but also replicates emotional prosody in unseen languages under the same zero-shot setting. IndexTTS 2.5 achieves a 2.28 times improvement in RTF while maintaining comparable WER and speaker similarity to IndexTTS 2.